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Polysubstituted derivatives of naphtalene, their process of preparation and their application in the cosmetic and pharmaceutical fields

机译:萘的多取代衍生物,其制备方法及其在化妆品和制药领域的应用

摘要

New polysubstituted derivatives of naphthalene. These derivatives correspond to the following formula: ##STR1## in which: R.sub. 1 to R.sub. 4 is H or CH.sub.3PPR.sub.5 is ##STR2## or (iv) the radical: 2-oxazolinyl m is 0 or 1PPR.sub.8.sbsb. r is H, alkyl, OR.sub.11, R.sub.11 being H, alkyl or ##STR3## R.sub.13 being alkyl or aryl or R.sub.8 is ##STR4## when m=1, r' and r" representing H, alkyl mono or polyhydroxyalkyl, aryl or a heterocycle when they are taken together, R.sub.9 is H or alkyl, R.sub.10 is H, alkyl and the acetals of the said compounds ##STR5## --OR.sub.14, R.sub.14 being H, alkyl, mono or polyhydroxyalkyl, aryl or aralkyl a rest of a sugar or represents ##STR6## being 0, 1, 2 or 3 R.sub.6 represents a hydrogen atom or a lower alkyl radical,PPR.sub.7 represents H, alkyl, halogen, hydroxyl, sulfydryl, alkoxy, alkylthio, acyloxy, acylthio, acylamino or primary, secondari or tertiary amino and the salts of the said compounds. PPThese compounds find an application in the cosmetic and pharmaceutical fields.
机译:萘的新的多取代衍生物。这些导数对应于以下公式:## STR1 ##其中:R.sub。 1至R.sub。 4是H或CH.sub.3 P sub.5是## STR2 ##或(iv)基团:2-恶唑啉基m是0或1 P .8.sbsb。当m为m时,r为H,烷基或OR11,R11为H,烷基或## STR3 ## R13为烷基或芳基或R8为## STR4 ## = 1,r'和r“表示H,烷基单或多羟基烷基,芳基或杂环,当它们合在一起时,R.sub.9是H或烷基,R.sub.10是H,烷基和所述化合物## STR5 ## --OR.sub.14,R.sub.14是H,烷基,单或多羟基烷基,芳基或芳烷基,其余为糖,或表示## STR6 ##为0、1、2或3个R 6代表氢原子或低级烷基,P 7代表H,烷基,卤素,羟基,巯基,烷氧基,烷硫基,酰氧基,酰硫基,酰氨基或伯,仲氨基或叔氨基以及所述化合物的盐这些化合物在化妆品和药物领域中得到应用。

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