PYRROLIDONE DERIVATIVE, ITS PRODUCTION AND ANTIAMNESIC AGENT CONTAINING PYRROLIDONE DERIVATIVE

摘要

NEW MATERIAL:A compound expressed by formula I {R is formula II to VI [Py is (substituted) pyridyl; Ph is (substituted) phenyl; R1 is halogen, alkyl or alkoxy; X is -SO2- or -CO-, provided that R1 is alkyl or alkoxy when X represents -SO2-]}. EXAMPLE:1-(3'-Nicotinoyl)-2-pyrrolidone. USE:An antiamnesic agent. PREPARATION:A compound expressed by the formula R-Z (Z is halogen) is reacted with N-trimethylsilyl-2-pyrrolidone, preferably in a solvent such as chloroform or THF at 15-50 deg.C within 72hr.