ANGIOTENSINASE ACTIVITY INHIBITOR CONTAINED IN LEGUMINOUS PLANT SEED

摘要

PURPOSE:To provide the title inhibitor, an extract from leguminous plant seeds which gives hypotensive activity through angiotensinase inhibition. CONSTITUTION:The objective substance giving angiotensinase inhibitory activity can be obtained by purifying, using, e.g. ion exchange chromatography, an extract from seeds of leguminous plant(s) such as kidney beans, white beans, red beans, cowpeas, red peas, soybeans, black soybeans, etc. For the extract from each kind of the above seeds, the measurement of 50% inhibitory concentration for the angiotensinase of rabbit lung origin was 5-25mug/ml.