首页> 外国专利> MONOCLONAL ANTIBODY AND METHOD FOR MEASURING PSEUDOLYSINE PHI USING SAID ANTIBODY

MONOCLONAL ANTIBODY AND METHOD FOR MEASURING PSEUDOLYSINE PHI USING SAID ANTIBODY

机译:利用所述抗体测定单克隆抗体和用于测定伪赖氨酸PHI的方法

摘要

PURPOSE:To easily and quickly discriminate the presence or absence of a progressive cancer or not by adding a monoclonal antibody to pseudolysine phito a specimen and measuring the generated composite pseudolysine phi-monoclonal antibody material. CONSTITUTION:An animal is immunized by using the pseudolysine phi and the spleen cells of the animal are sampled. The pseudolysine phi is conjugated to a carrier protein of bovine serum albumin, etc., and is then used as an immune source. The resultant spleen cells are made confluent with the myeloma cells to obtain a hybridoma. The pseudolysine phi is measured by using the monoclonal antibody produced from the resultant hybridoma, by which the presence or absence of the progressive cancer is easily and quickly discriminated.
机译:目的:通过向样品中的假赖氨酸添加单克隆抗体并测量所产生的复合假赖氨酸phi-单克隆抗体材料,轻松快速地区分是否存在进行性癌症。组成:使用伪赖氨酸phi对动物进行免疫,并采样动物的脾细胞。将假赖氨酸phi与牛血清白蛋白等的载体蛋白缀合,然后用作免疫源。使所得的脾细胞与骨髓瘤细胞汇合以获得杂交瘤。通过使用由所得杂交瘤产生的单克隆抗体来测量假赖氨酸phi,通过该单克隆抗体可以容易且快速地区分进行性癌症的存在与否。

著录项

  • 公开/公告号JPH0421479B2

    专利类型

  • 公开/公告日1992-04-10

    原文格式PDF

  • 申请/专利权人 SENDAI BISEIBUTSU KENKYUSHO;

    申请/专利号JP19860143484

  • 申请日1986-06-19

  • 分类号C07K14/195;C07K14/005;C07K16/00;C12N5/00;C12N5/10;C12N15/00;C12N15/02;C12P21/00;C12P21/08;C12R1/91;G01N33/574;G01N33/577;

  • 国家 JP

  • 入库时间 2022-08-22 05:42:20

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