首页> 外国专利> ACQUIRING PROCESS FOR MONOCLONAL ANTIBODY, AND MEASURING PROCESS FOR COUPLING PRODUCT MADE OF BOTH BIOGEN AMINE AND COUPLING REAGENT, MONOCLONAL ANTIBODY AND 1ST OR 2ND CLASS BIOGEN AMINE

ACQUIRING PROCESS FOR MONOCLONAL ANTIBODY, AND MEASURING PROCESS FOR COUPLING PRODUCT MADE OF BOTH BIOGEN AMINE AND COUPLING REAGENT, MONOCLONAL ANTIBODY AND 1ST OR 2ND CLASS BIOGEN AMINE

机译:单克隆抗体的获取过程,以及生物素胺与试剂,单克隆抗体和一,二类生物素偶合剂的偶联产物的测定过程

摘要

The invention relates to a process for obtaining a monoclonal antibody against a primary or secondary biogenous amine, where the antibody is directed against a coupling product of the biogenous amine and a coupling reagent, wherein a primary or secondary amine is bonded via its amino group to a coupling reagent whose reactive group is an iso(thio)cyanato group, the coupling product is bound to a carrier material, and the bound coupling product is used as immunogen. Furthermore, the invention also relates to a method for the immunological determination of biogenous amines with the aid of the antibodies against the coupling product.
机译:本发明涉及获得针对伯或仲生物胺的单克隆抗体的方法,其中所述抗体针对所述伯胺和偶联剂的偶联产物,其中伯或仲胺通过其氨基键合至一种偶合试剂,其反应性基团是异(硫)氰酸根合基团,该偶合产物结合到载体材料上,并且该结合的偶合产物用作免疫原。此外,本发明还涉及借助针对偶联产物的抗体免疫测定生物胺的方法。

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