PREVENTION OF OSTEOPOROSIS AND REMEDY FOR OSTEOPOROSIS

摘要

PURPOSE:To obtain the subject formulation containing imidazo-[4,5-C] quinoline-4-one derivative or acid-added salt of said derivative as an active ingredient. CONSTITUTION:The subject formulation contains a compound expressed by the formula or pharmacologically allowable acid-added salt of the compound (R1 is H or lower alkyl; R2 is H, OH or SH; R3 is lower alkyl or lower alkoxyalkyl). The compound expressed by the formula has excellent bone resorption activity and is useful for prevention and curing of osteoporosis. The compound expressed by the formula or acid-added salt of the compound is uniformly mixed with a carrier and prepared to an unit taking shape suitable for administration by per as such as tablet or capsule, or injection. Administration dose of the compound expressed by the formula is usually 20-100mg/person per 1 day.