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HIDTIL UKENDTE BENZOFURANDERIVATER, EN FREMGANGSMAADE TIL DERES FREMSTILLING OG FARMACEUTISKE ELLER VETERINAERE MIDLER INDEHOLDENDE ET SAADANT DERIVAT
HIDTIL UKENDTE BENZOFURANDERIVATER, EN FREMGANGSMAADE TIL DERES FREMSTILLING OG FARMACEUTISKE ELLER VETERINAERE MIDLER INDEHOLDENDE ET SAADANT DERIVAT
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机译:永久性苯并呋喃衍生物,其制备方法以及含有此类衍生物的药物或兽药措施
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摘要
Benzofuran derivatives represented by the general formula: IMAGE in which: R represents an ethyl, n-propyl, isopropyl or n-butyl radical; R1 represents a branched-chain alkyl radical having from 4 to 7 carbon atoms of which at least one does not bear a hydrogen atom; R2 represents hydrogen, chlorine or bromine; n is 1 or 2 and pharmaceutically acceptable acid addition salts thereof. These derivatives have been found to possess calcium translocation inhibiting properties and antiadrenergic properties and can thus be used in the treatment of certain pathological syndromes of the cardiovascular system.
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机译:由通式:表示的苯并呋喃衍生物,其中:R代表乙基,正丙基,异丙基或正丁基。 R 1表示具有4至7个碳原子的支链烷基,其中至少一个不带有氢原子; R 2代表氢,氯或溴; n为1或2及其药学上可接受的酸加成盐。已经发现这些衍生物具有抑制钙转运的特性和抗肾上腺素能,因此可以用于治疗心血管系统的某些病理综合症。
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