PSYCHOGERIATIC DIAZINYLPIPERIDINE DERIVATIVES OF CYCLIC AMIDES AND IMIDES

摘要

Nootropic compounds of Formula I IMAGE wherein X is an ethylene chain or a 1,2-benzo ring; Y is carbonyl or methylene; R1 is hydrogen or lower alkyl; and Z is an R2, R3-disubstituted diazinyl ring selected from pyridazine, pyrimidine, and pyrazine ring systems, where R2 and R3 are selected from H, C1-4 alkyl, alkoxy or alkylthio, CN, CF3, C2F5 or halogen, possess cognition and memory enhancing activity.