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LEUSTRODUXINE DERIVATIVES, PRODUCTION AND THERAPEUTICAL APPLICATION THEREOF
LEUSTRODUXINE DERIVATIVES, PRODUCTION AND THERAPEUTICAL APPLICATION THEREOF
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机译:乐土杜松衍生物,生产及其治疗应用
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摘要
New compounds, which we have named the "Leustroducsins" have the formula (I): CHEM in which R represents a 5-methylhexanoyloxy group, a 6-methyloctanoyloxy group or a 7-methyloctanoyloxy group, and salts thereof, and may be prepared by fermentation using a microorganism of the genus Streptomyces, especially a strain of the species Streptomyces platensis, such as strain SANK 60191 (FERM BP-3288). These compounds may be used for the treatment or prophylaxis of: adverse reactions resulting from cancer chemotherapy or radiotherapy; infections; cancer; cerebral dysfunction; and fungal infections.
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