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AGISTATINS,NOVEL METABOLITES FROM FUSARIUM SP.,A PROCESS FOR THEIR PREPARATION AND THEIR USE
AGISTATINS,NOVEL METABOLITES FROM FUSARIUM SP.,A PROCESS FOR THEIR PREPARATION AND THEIR USE
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机译:烟曲霉毒素,来自镰刀菌属的新型代谢物,其制备和使用方法
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摘要
It is possible with the aid of a Fusarium strain to prepare metabolites of the following formula I IMAGE in which R1 is hydrogen or hydroxyl, R2 is hydroxyl or an oxo group, R3 is methoxy or hydroxyl or, together with R1, forms an ether bridge and R4 is hydrogen or hydroxyl, R5 is hydrogen or, together with R4, represents an additional bond and R6 is hydrogen or, together with R3, is an additional bond. The metabolites are to be used, in particular, for inhibiting cholesterol biosynthesis.
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