首页>
外国专利>
CELL LINE AND MONOCLONAL ANTIBODY WHICH BINDS TO A SPECIFIC ANTIGENIC SITE EXPRESSED ON THE SURFACE OF PHAGOCYTIC CELLS
CELL LINE AND MONOCLONAL ANTIBODY WHICH BINDS TO A SPECIFIC ANTIGENIC SITE EXPRESSED ON THE SURFACE OF PHAGOCYTIC CELLS
展开▼
机译:绑定到在噬菌体表面表达的特定抗原原位点的细胞系和单克隆抗体
展开▼
页面导航
摘要
著录项
相似文献
摘要
A hybrid cell line is developed which produces a monoclonal antibody which binds to a unique antigenic site expressed on the surface of phagocytic cells. The monoclonal antibody binds to and activates a specific domain of the CD11b glycoprotein so as to inhibit adhesion dependent functions of the phagocytic cell, but it does not affect other phagocytic functions. This monoclonal antibody can be used as a reactant in an in vitro diagnostic immunoassay for detecting the unique antigenic site on the surface of normal human neutrophils.
展开▼