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METHOD OF, AND APPARATUS FOR NMR SPECTROSCOPIC METABOLITE IMAGING AND QUANTIFICATION

机译:NMR光谱代谢物成像和定量的方法和装置

摘要

A method for NMR spectroscopy metabolite imaging utilizes the steps of: applying to a desired portion of a sample a pulsed phase- encoding linear magnetic gradient signal in at least one of the three orthogonal dimensions of a Cartesian coordinate set, prior to acquisition of free- induction-decay NMR response signals from the sample portion; substantially eliminating from at least the sample portion eddy current fields induced responsive to the phase-encoding gradient pulses; maximizing the signal-to-noise ratio of the NMR response signals; and displaying the data resulting from Fourier transformation of the received response data. A high-field NMR imaging system is provided with self- shielded gradient coils, to subsantially remove eddy-current effects, and at least one of maximized-SNR antenna, of quadrature-driven volume RF coil and/or surface RF coil types are utilized for both transmission of the excitation RF pulses and reception of the RF response signals. The acquired FID data is filtered and a Fourier transform reconstruction, of dimension d' equal to one greater than the numder d of spatial dimensions to be displayed, is performed.
机译:NMR光谱代谢物成像的方法采用以下步骤:在采集自由原子之前,在笛卡尔坐标集的三个正交维度中的至少一个维度上,将脉冲相位编码线性磁梯度信号应用于样品的所需部分,来自样品部分的感应衰减NMR响应信号;从至少样品部分基本上消除了响应于相位编码梯度脉冲而感应的涡流场;最大化NMR响应信号的信噪比;显示接收到的响应数据的傅立叶变换得到的数据。一种具有自屏蔽梯度线圈的高场NMR成像系统,以基本消除涡流效应,并且使用正交驱动的体积RF线圈和/或表面RF线圈类型中的至少一种,即最大SNR天线。用于发射激励射频脉冲和接收射频响应信号。过滤所获取的FID数据,并且执行尺寸d'等于要显示的空间尺寸的数字d的一的傅立叶变换重构。

著录项

  • 公开/公告号IL91955B

    专利类型

  • 公开/公告日1992-07-15

    原文格式PDF

  • 申请/专利权人 GENERAL ELECTRIC COMPANY;

    申请/专利号IL91955

  • 发明设计人

    申请日1989-10-12

  • 分类号G01N;

  • 国家 IL

  • 入库时间 2022-08-22 05:35:12

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