METHOD FOR INCREASING THE RESPONSE IMMUNE TO NEISSERIA MENINGITIDIS EXTERNAL MEMBRANE CLASS II PROTEIN ANTIGENS

摘要

34/JWW14 35/JWW15 18160IA TITLE OF THE INVENTION THE CLASS II PROTEIN OF THE OUTER MEMBRANE OF NEISSERIA MENINGITIDIS HAVING IMMUNOLOGIC CARRIER AND ENHANCEMENT PROPERTIES The Class II major immuno-enhancing protein (MIEP) of Neisseria meningitidis, purified directly from the outer membrane of Neisseria meningitidis, or obtained through recombinant cloning and expression of DNA encoding the MIEP of Neisseria meningitidis, has immunologic carrier as well as immunologic enhancement, cytokine-inducing (such as interleukin-2 (I1-2)) and mitogenic properties.