INHIBITION OF INTERLEUKIN-1 BY MONOCYTES AND/OR MACROPHAGES

摘要

ABSTRACT OF THE DISCLOSUREA method of inhibiting the production ofinterleukin-1 by monocytes and/or macrophages in a humanin need thereof which comprises administering to suchhuman an effective interleukin-1 production inhibitingamount of a diaryl-substituted imidazole fused to athiazole, pyrrolidine or piperidine ring or apharmaceutically acceptable salt thereof.