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Use of 2,3-disubstituate 1-azolyl-propane for inhibiting the pathogenic growth phase of dimorph yeast cell
Use of 2,3-disubstituate 1-azolyl-propane for inhibiting the pathogenic growth phase of dimorph yeast cell
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机译:2,3-二取代的1-偶氮基丙烷在抑制双形酵母细胞致病性生长阶段中的应用
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摘要
Compounds of the formula I IMAGE with A equal to CH, N; X equal to -NR(1)R(2)-O-phenyl-, O-benzyl-, S-phenyl, -S-benzyl, O-N=R(3)R(4), with R(1) equal to (cyclo)alk(en)yl, (alkyl)phenyl, (alkyl)hetaryl and others and R(2) equal to hydrogen or R(1); or R(1) and R(2) together a chain (CH2)4-6; R(3) equal to phenyl, biphenylyl, phenylmethylphenyl, phenyl-Z-phenyl, benzyl, alkyl and Z equal to oxygen, sulphur, sulph(i)(o)nyl and R(3) equal to alk(en)(yn)yl, phenyl, benzyl Y equal to OH, SH, Hal, Z-R(5) with R(5) equal to (cyclo)alk(en)yl, alkylphenyl, alkyl, hetaryl, biphenylyl, phenyl-Z-phenyl, phenylmethylphenyl, naphthyl are outstandingly suitable for the prophylaxis and treatment of systemic mycoses.
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