METHOD OF 2,3A-DIHYDOXY-3-BENZOL-3A,4-DIHYDRO-1H-PYRROLO-2,1-C-1,4- BENZOXAZINE-1,4-DIONE SYNTHESIS

摘要

Use: as anti-inflammatory compounds. SUMMARY OF THE INVENTION: Product: 2,3a-dihydroxy-3-benzoyl-3a, 4-digid- ro-1 H-pyrrolo s11,4 2,1-benzoxazin-1,4-dione, BF CisHnNOe, mp.. 120-2 & amp; deg; C, yield 92%. Reagent 1, 3-fenatsiliden-1,4-benzoxazin-2-one. Reagent 2: oxalic acid dichloride. Reaction conditions: th aprotonno- solvent under an inert atmosphere at reflux followed by treating the precipitate with water.