Derivatives of ((n - (alkylamino - 2 oxo - 2 ethyl) -methylamino) ethyl) - 5 - 2 - 3 hydroxyl (phenyl) methoxy - 4 - 2 are - 2,3 5h - benzothiazepine - 1,5 one - 4, their preparation and their application of international application no.

摘要

Compounds in the form of pure diastereoisomers or of mixtures thereof, corresponding to the general formula (I) …IMAGE… in which R1 represents a hydrogen atom or a C2-C4 alkanoyl group, R2 and R3, independently of one another, each represent a hydrogen atom, a linear or branched C1-C4 alkyl group, a C3-C5 cycloalkyl group, a phenyl group, a benzyl group or a phenethyl group, or alternatively R2 and R3, together with the nitrogen atom which carries them, form a heterocycle chosen from substituted or unsubstituted pyrrolidinyl, substituted or unsubstituted piperidyl, 1,2,3,6-tetrahydropyridyl, perhydroazepinyl, perhydroazocinyl, 1,3-thiazolidinyl, thiomorpholinyl, morpholinyl, 2,3-dihydroindolyl, substituted or unsubstituted 1,2,3,4-tetrahydroisoquinolyl or 2,3,4,5-tetrahydro- 1H-benzo[b]azepinyl groups, and X represents a hydrogen or chlorine atom. Use in therapy.