AMINO-4 AROYL-3 QUINOLEINS AND NAPHTYRIDINES, THEIR PREPARATION PROCESS AND THEIR APPLICATION IN THERAPEUTICS

摘要

The compounds of the invention correspond to the following formula: IMAGE in which R1 and R2, which are identical or different, represent a hydrogen atom, a C1 to C6 alkyl group or a phenyl or benzyl group, or else R1 and R2 can form, with a nitrogen atom to which they are attached, a saturated C4 to C8 heterocycle which can contain a second heteroatom such as oxygen, sulphur or nitrogen, R3 represents a hydrogen atom or a C1 to C6 alkyl or benzyl group, R4 represents a hydrogen atom or a C1 to C6 alkyl group, R5 represents a hydrogen atom, a halogen atom or a C1 to C6 alkyl, C1 to C4 alkoxy, nitro or trifluoromethyl group, n is equal to 0, 1 or 2, Ar represents an aromatic or heteroaromatic group, and A, B, C and D each represent CH or one of them represents N and the others CH.