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Intracellular antigen found in subpopulation of CD8.sup.+ T lymphocytes and monoclonal antibody reactive with same
Intracellular antigen found in subpopulation of CD8.sup.+ T lymphocytes and monoclonal antibody reactive with same
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机译:CD8 + T淋巴细胞亚群中发现的细胞内抗原和与之反应的单克隆抗体
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摘要
A 15 kd protein antigen is associated with cytoplasmic granules in cytolytic T lymphocytes and natural killer cells. Monoclonal antibodies immunologically reactive with the 15 kd protein and nucleic acid probes encoding polypeptides that are immunologically cross-reactive with the 15 kd protein can be used, e.g., to identify cytolytic lymphocytes in a sample. Cloned cDNA encoding the antigen can be used to produce the antigen.
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