Apparatus and method for dynamic blanking of non-specific light scattering during rate nephelometric reactions

摘要

A scatter signal is produced from light scattered by a precipitate formed by a chemical reaction and non-specific scatter sources. A blanking signal is produced from light scattered only by the non-specific scatter sources that contribute to the scatter signal, and the blanking signal is subtracted from the scatter signal to dynamically produce a signal indicative of the difference between the scatter signals to reduce the effects of non-specific scattering sources in determining the rate of change of the light scattered by the precipitate. One of the scatter signals may be stored and then combined with the other, or the signals may be measured simultaneously and then combined.