SYNERGISTIC MEDICINE COMBINATION AND DRUG COMPOSITION IN TREATMENT OF ANXIETY

摘要

PURPOSE: To prepare a synergistic combination in treating anxiety and a drug composition for treating anxiety comprising the combination. CONSTITUTION: This combination comprises a first component selected from the group consisting of 8-hydroxy-2-(dipropylamino)-tetralin, gepirone, ipsapirone, tandospirone, (7S,9S)-2-(2-pyrimidyl)-7-succinimidomethyl)-perhydro-1H-pyrido[1,2- a]pyrazine or chlordiazepoxide and a second component selected from the group consisting of 1-(2-pyrimidyl)pyrazine and idazoxan and has synergistic anxiolytic activities. Furthermore, a drug composition for treating anxiety comprises the combination.