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PEPTIDE AMIDE AND AMIDE DIMER

机译:肽酰胺和酰胺二聚体

摘要

Peptide amide and amide dimer muscle relaxants represented by the formulae: CHEM wherein: R is lower alkyl; R1 and R2 independently selected from the group consisting of hydrogen, lower alkyl, allyl, propargyl, aryl lower alkyl and cyclo-lower alkyl lower alkyl, or R plus one or both of R1 and R2, together with the nitrogen to which they are attached, form a heterocyclic ring having 5 to 7 member atoms; AA are independently selected from certain amino acids moieties; n is 2 to 4; x is independently 0 or 1; y is independently 1 or 2; z is 2 to 12; and and An- is a pharmaceutically acceptable anion.
机译:由下式表示的肽酰胺和酰胺二聚体肌肉松弛剂:<化学式>其中:R为低级烷基; R1和R2独立地选自氢,低级烷基,烯丙基,炔丙基,芳基低级烷基和环低级烷基低级烷基,或R加上R1和R2之一或两者,以及它们所连接的氮形成具有5至7个成员原子的杂环; AA独立地选自某些氨基酸部分; n为2至4; x独立为0或1; y独立为1或2; z是2到12;和An-是药学上可接受的阴离子。

著录项

  • 公开/公告号JPH0570420A

    专利类型

  • 公开/公告日1993-03-23

    原文格式PDF

  • 申请/专利权人 B O C HEALTH KEA INC;

    申请/专利号JP19920018764

  • 申请日1992-02-04

  • 分类号C07C237/22;A61K31/16;A61K37/02;C07K5/06;C07K5/08;C07K5/10;

  • 国家 JP

  • 入库时间 2022-08-22 05:15:41

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