Peptide amide and amide dimer muscle relaxants represented by the formulae: wherein: R is lower alkyl; R₁ and R₂ independently selected from the group consisting of hydrogen, lower alkyl, allyl, propargyl, aryl lower alkyl and cyclo-lower alkyl lower alkyl, or R plus one or both of R₁ and R₂, together with the nitrogen to which they are attached, form a heterocyclic ring having 5 to 7 member atoms; AA are independently selected from certain amino acids moieties; n is 2 to 4; x is independently 0 or 1; y is independently 1 or 2; z is 2 to 12; and and An⁻ is a pharmaceutically acceptable anion.
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机译:下式表示的肽酰胺和酰胺二聚体肌肉松弛剂: <图像文件=“ IMGA0001.GIF” he =“ 52” imgContent =“ chem” imgFormat =“ GIF” wi =“ 145” /> Chemistry> 其中:R为低级烷基; R 1和R 2独立地选自氢,低级烷基,烯丙基,炔丙基,芳基低级烷基和环低级烷基低级烷基,或R加上R 1和R 2中的一个或两个,以及它们所连接的氮。形成具有5至7个成员原子的杂环; AA独立地选自某些氨基酸部分; n为2至4; x独立为0或1; y独立为1或2; z是2到12;并且An +是药学上可接受的阴离子。
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