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10,11,12,13-TETRAHYDRODESMYCOSINE DERIVATIVE, ITS PRODUCTION AND ITS USE AS MEDICINE
10,11,12,13-TETRAHYDRODESMYCOSINE DERIVATIVE, ITS PRODUCTION AND ITS USE AS MEDICINE
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机译:10,11,12,13-四氢脱氢美沙因衍生物,其生产及其作为药物的用途
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摘要
The invention relates to derivatives of 10,11,12,13-tetrahydro-desmycosin, CHEM wherein R stands for O or (OC2H5)2, R1 stands for Si(CH3)3 or H, R2 stands for H, OH, I or OSO2CH3, which are novel semisynthetic antibiotics of the tylosin series, possessing antibacterial activity, to their pharmaceutically acceptable salts with inorganic or organic acids, to processes for their preparation and to their use in obtaining pharmaceutical preparations.
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机译:本发明涉及10,11,12,13-四氢-脱粘菌素的衍生物,其中R代表O或(OC 2 H 5)2,R 1代表Si(CH 3)3或H,R 2。代表H,OH,I或OSO2CH3,它们是泰乐菌素系列的新型半合成抗生素,对它们与无机或有机酸的药学上可接受的盐,其制备方法以及在获得药物制剂中的使用具有抗菌活性。
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