NEW 14-CROWN-4-ETHER DERIVATIVE AND ITS PREPARATION

摘要

PURPOSE: To provide a new compound useful in clinical chemistry, etc., which is used to make the dry analytical element for quantitatively assaying lithium in serum. ;CONSTITUTION: The compound of formula I [R is n-C₁₂H₂₅, CH₃, CH₂C₆H₅; R₁ is H, NO₂, SO₂CH₃, SO₂N(n-C₆H₁₃)₂, SO₂N(CH₃)-n-C₁₈H₃₇; R₂ is CH₃, n-C₇H₁₅; X is CH or N], e.g. 6-[2-hydroxy-5-((p)-nitroarylazo)benzyl]-1,4,8,11- tetraoxacyclotetradecane, is obtained by allowing a compound of formula II to react with a compound of formula III.;COPYRIGHT: (C)1993,JPO