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GRF-analogous peptides, pharmaceutically acceptable salts thereof and methods for preparing these

机译:GRF类似肽,其药学上可接受的盐及其制备方法

摘要

The present invention relates to novel growth hormone-releasing peptides and method for increasing the release of growth hormone levels in mammals. The novel peptides of this invention surprisingly are effective for releasing growth hormone levels in animals by replacing the natural amino acids in positions 1, 2 and 3, as well as derivatizing the N-terminal amino acid residue in human pancreatic islet tumor origin growth hormone-releasing factor.
机译:本发明涉及新颖的生长激素释放肽和用于增加哺乳动物中生长激素水平释放的方法。令人惊讶的是,本发明的新肽通过取代1、2和3位的天然氨基酸,以及衍生人胰岛肿瘤起源的生长激素-中的N-末端氨基酸残基,有效地释放了动物体内的生长激素水平。释放因子。

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