PROCESS FOR PRODUCING LOCALLY APPLICABLE PHARMACEUTICAL COMPOSITIONS COMPRISING COLLAGENASE IN LARGE DOSE

摘要

This invention provides pharmaceutical compositions for topical application containing high concentrations of the enzyme collagenase in non-aqueous excipients. The invention also provides a particular excipient, dextran, which is especially useful for admixture with collagenase and which can also be used to advantage with uother pharmaceutically active materials.