首页> 外国专利> BLOOD FACTORS PRODUCED BY RECOMMBINANT PROCESS, PROCESS FOR EXPRESSING THEM, AS WELL AS RECOMBINANT VACCINE VIRUSES USED IN THE PROCESS

BLOOD FACTORS PRODUCED BY RECOMMBINANT PROCESS, PROCESS FOR EXPRESSING THEM, AS WELL AS RECOMBINANT VACCINE VIRUSES USED IN THE PROCESS

机译:重组过程产生的血液因子,表达它们的过程以及该过程中使用的重组疫苗病毒

摘要

Recombinantly produced blood factors as well as a process for their preparation are described, said blood factors having a ratio of biologically active form to antigenic form of at least 50 %, preferably in the range of 60 to 90 %. There are also disclosed recombinant vaccinia viruses used in the above process. The process according to the invention provides an improved expression system with high post-translational capacity under stable expression conditions.
机译:描述了重组产生的血液因子及其制备方法,所述血液因子的生物活性形式与抗原形式的比率为至少50%,优选在60%至90%的范围内。还公开了在上述方法中使用的重组牛痘病毒。根据本发明的方法提供了在稳定表达条件下具有高翻译后能力的改进的表达系统。

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