ISOLATED AND PURIFIED DNA SEQUENCES CODING ANTIGEN EXPRESSED BY TUMOR CELLS AND RECOGNIZED BY CYTOTOXIC T CELLS,AND USES THEREOF

摘要

The invention relates to an isolated DNA sequence which codes for an antigen expressed by tumor cells which is recognized by cytotoxic T cells, leading to lysis of the tumor which expresses it. Also described are cells transfected by the DNA sequence, and various therapeutic and diagnostic uses arising out of the properties of the DNA and the antigen for which it codes.