SYNTHETIC PEPTIDES WHICH INDUCE CELLULAR IMMUNITY TO THE AIDS VIRUS AND AIDS VIRAL PROTEINS, THEIR PREPARATION AND USE

摘要

Identification of short peptide segments of AIDS virus proteins which elicit T cellular immunity, and method of inducing cellular immunity to native proteins of the AIDS virus by immunization with short synthetic peptides. Five potential peptides have been identified by searching for regions which can fold as a maximally amphipathic helix. These may be useful to include in either a synthetic peptide- or recombinant fragment-based vaccine.