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ANTI-HUMAN UROKINASE MONOCLONAL ANTIBODIES AND THEIR USE IN PURIFYING OR DETECTING HUMAN UROKINASE
ANTI-HUMAN UROKINASE MONOCLONAL ANTIBODIES AND THEIR USE IN PURIFYING OR DETECTING HUMAN UROKINASE
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机译:抗人尿激酶单克隆抗体及其在纯化或检测人尿激酶中的用途
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摘要
A class of new IgG1 monoclonal antibodies, directed to an epitope on human urokinase, which selectively bind to high molecualr weight urokinase (54,000), or a single-chain precursor thereof, without binding to low molecular weight urokinase (33,000) have an affinity constant for urokinase which is suitable for use in an immono-adsorption-based purification system and does not impair the enzymatic activity of urokinase. This antibody is also useful in immunoassays.
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