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SPECIFIC PARENTERICAL EMULSES CONTAINING LIPOFILIC AND / OR DERIVATIVE LIPOPHILIC DERIVATIVES AND THE DERIVATIVES OF PHENANTREN AS AN EMULSIFYING AGENT AND ITS USE OF X-RAY CONTRAST COMOAGENTS
SPECIFIC PARENTERICAL EMULSES CONTAINING LIPOFILIC AND / OR DERIVATIVE LIPOPHILIC DERIVATIVES AND THE DERIVATIVES OF PHENANTREN AS AN EMULSIFYING AGENT AND ITS USE OF X-RAY CONTRAST COMOAGENTS
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机译:包含脂蛋白和/或衍生脂蛋白衍生物和菲衍生物作为乳化剂的特定准寄生物及其在X射线造影剂中的应用
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PCT No. PCT/SE92/00261 Sec. 371 Date Dec. 7, 1993 Sec. 102(e) Date Dec. 7, 1993 PCT Filed Apr. 22, 1992 PCT Pub. No. WO92/18169 PCT Pub. Date Oct. 29, 1992.Disclosed are emulsions for intravenous administration based on lipophilic iodized and/or bromated substances with emulsifiers and containing derivatives of cyclopenta-phenanthrene, wherein the weight ratio between emulsifier and derivative in the emulsion is between 10:1 and 1:2. These emulsions are intended for use as X-ray contrast agent, particularly for visibilizing the presence of tumors, metastases and the like in liver and spleen. The derivative of cyclopenta-phenanthrene is preferably cholesterol, phytosterol, sitosterol, sigmasterol and/or campesterol. The invention also relates to a method for preparing the emulsion and to the use of the emulsion in the preparation of an X-ray contrast medium for computed tomographic examinations.
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