synthesis of pyrazole diaryle regioselective anti-inflammatory agents.

摘要

the invention provides a process for the preparation of anti-inflammatory agents pyzarole diaryle - 1.5.an acid dioxohexanoique - 6 - 4 - aryl - 6 deals with hydrogen peroxide or acetyl chloride to produce an enol lactone.is added to the hydroxamic acid to generate methylhydroxylamine dione.the hydroxamic acid is treated with 4 - dione, methoxyphenylhydrazine hydrochloride to give the pyrazole diaryle - 1.5.new intermediate compounds are also found within the see