首页>
外国专利>
medicaments and preparations ahead of dihydrochloride of melarsomina process for their production and intermediate products obtained
medicaments and preparations ahead of dihydrochloride of melarsomina process for their production and intermediate products obtained
展开▼
机译:生产黑麦草素工艺的药物和制剂比黑麦草素工艺更早
展开▼
页面导航
摘要
著录项
相似文献
摘要
The medicinal product comprises as active principle a melarsomine hydrochloride preparation having a purity of between 98.5 and 100%. The process for obtaining this preparation is stated essentially as follows: step 1, trichlorotriazine (TCT) is converted to diaminochlorotriazine (DCT) in an ammoniacal medium; step 2, the DCT is converted to melarsen acid hydrochloride (MAH) in the presence of arsanilic acid; step 3, the MAH is reduced to melarsen oxide dihydrate; and step 4, the melarsen oxide dihydrate is converted to melarsomine dihydrochloride in the presence of cysteamine hydrochloride. In each step, a purified preparation of the corresponding intermediate product, or final product in step 4, is obtained.
展开▼