PROCESS FOR THE SYNTHESIS OF 5-(SUBSTITUTED)-AMINO-8- PHENYL OR SUBSTITUTED-PHENYL-3H, 6H-1, 4, 5A, 8A-TETRAAZAACENAPHTHYLEN-3-ONES

摘要

31,808-00 AN IMPROVED PROCESS FOR THE SYNTHESIS OF 5-¢(SUBSTITUTED)AMINO!-8-¢PHENYL OR SUBSTITUTED-PHENYL!-3H,6H-1,4,5a,8a- TETRAAZAACENAPHTHYLEN-3-ONES A novel process for producing 5¢(substituted)amino!-8-¢phenyl or substitutedphenyl!-3H,6H-1,4,5a,8a-tetraazaace-napthylen-3-ones of the formula: Where R1, R2 and R3 are defined in the specification by reacting a 4,5-dihydro-7-¢phenyl or substituted phenyl!pyrazolo¢1,5-a!pyrimidine-3-carboxaminde with carbon disulfide and a suitable base and a lower alkyl iodide to give a 5-(lower alkylthio)-8-¢phenyl or substituted phenyl!-3H,6H-1,4,5a,8a-tetraazaacenphth-ylen-3-one which is further reacted with an amine of the formula: to give the desired compounds.