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METHOD FOR GENETICALLY MODIFYING BONE MARROW CELLS OF PRIMATES, AND USEFUL CELLS THEREFOR THAT PRODUCE RECOMBINANT RETROVIRAL VECTORS
METHOD FOR GENETICALLY MODIFYING BONE MARROW CELLS OF PRIMATES, AND USEFUL CELLS THEREFOR THAT PRODUCE RECOMBINANT RETROVIRAL VECTORS
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机译:遗传修饰原始骨髓细胞的方法,以及产生重组逆转录病毒载体的有用细胞
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摘要
2120370 9307281 PCTABS00021 A method for genetically modifying bone marrow cells of primates, comprising isolating bone marrow cells from a primate and, by means of cocultivation, exposing the isolated bone marrow cells to cells that produce a recombinant amphotropic retrovirus with a genome based on a retroviral vector that contains the genetic information to be introduced into the bone marrow cells. Recombinant amphotropic retrovirus-producing cells, suitable for use in this method.
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