SYNTHESIS AND PURIFICATION OF TRUNCATED AND MUTEIN FORMS OF HUMAN CILIARY NEURONOTROPHIC FACTOR

摘要

2123234 9310233 PCTABS00022 The present invention relates to truncated and mutein forms of human ciliary neuronotrophic factor, nucleic acid sequences which encode these forms, the amino acid sequences of these forms, methods of producing the same by means of recombinant DNA techniques, pharmaceutical compositions containing these truncated and mutein forms of CNTF, and methods of use thereof.