C1 INHIBITOR VARIANTS AND TREATING INFLAMMATORY RESPONSE WITH C1 INHIBITOR

摘要

A method of treating a systemic inflammatory response in a mammal comprising administering to the mammal a therapeutically effective amount of C1-INH or C1-INH variant in an amount sufficient to treat the systemic inflammatory response. Among the acquired systemic inflammatory syndromes treated are hypotensive septic shock, adult respiratory distress syndrome, multiple organ system failure and preeclampsia.