MONOSACCHARIDE ANALOG-BASED GLYCOSIDASE INHIBITORS

摘要

Broad spectrum glycosidase inhibitors are produced from monosaccharide lactams by conversion to amidines, amidrazones, or amidoximes. The inhibitors have general formula (I), wherein the N and C are joined as part of a monosaccharide aza-analog ring and wherein -NRQ, together with the nitrogen and carbon atoms, form a chemical group selected from amidines, amidrazones, and amidoximes.