Method and device for making a two-dimensional image of a determined activity distribution in a three-dimensional body along a determined section through that body by restoring a two-dimensional image that has been reconstructed from projections of this activity distribution obtained using an activity detector, using an artificial neural network, wherein in a first step the neural network is trained by supplying to the output thereof at least one set of data corresponding with one determined simulated activity distribution and by supplying to the input thereof a set of data which data corresponds with a two-dimensional image that has been reconstructed from simulated projections of this simulated activity distribution, and in a second step data is supplied to the input of the thus trained network which corresponds with the two-dimensional images reconstructed from the obtained projections.
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