PREVENTION OF DRUG-INDUCED AGRANULOCYTOSIS WITH FREE RADICAL SCAVENGERS

摘要

A method is provided of preventing an occurence of granulocytopenia or agranulocytosis as a drug-induced side effect in a patient. The method entails co-administering to the patient (1) an active drug other than clozapine with which granulocytopenia or agranulocytosis is a possible side effect, and (2) an effective amount of a free radical scavenger for preventing the occurence of the side effect. Pharmaceutical preparations and kits containing the active drug and the free radical scavenger are also provided.