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A novel hypoglycemic and growth-promoting agent

机译:新型降血糖和促生长剂

摘要

This application discloses an invention comprising a polypeptide fraction isolated from commercial bacitracin and which contains most if not all of the anti-insulinase activity of bacitracin while exhibiting few if any of the antibacterial properties. The invention herein described also involves the use of this polypeptide fraction given orally. or if given parenterally either together (as composite) or in sequence as a means of treating diabetics. For such purposes, the insulin and anti-insulinase polypeptide fraction may be used as separate substances or chemically linked by ba wide variety of chemical linking agents well known in the art. In addition to clinical uses, the application describes a method of using the polypeptide fraction as a growth promoter substance to be added to animal feed and also a composition useful for this purpose.
机译:该申请公开了一种包含从商业杆菌肽分离的多肽级分的发明,该多肽级分包含杆菌肽的大多数(如果不是全部的话)抗胰岛素酶活性,而几乎没有抗菌性能。本文描述的本发明还涉及口服给予的该多肽级分的用途。或经胃肠外给予(作为复合物)或按顺序给予作为治疗糖尿病的手段。为此目的,胰岛素和抗胰岛素酶多肽级分可用作单独的物质或通过本领域众所周知的多种化学连接剂进行化学连接。除了临床用途之外,该申请还描述了使用多肽级分作为要添加到动物饲料中的生长促进剂物质的方法,以及用于该目的的组合物。

著录项

  • 公开/公告号EP0302445B1

    专利类型

  • 公开/公告日1992-11-11

    原文格式PDF

  • 申请/专利权人 THE PROTOR CO.;

    申请/专利号EP19880112533

  • 发明设计人 MEDINA VICTOR;STRACHER ALFRED;KESNER LEO;

    申请日1988-08-02

  • 分类号A61K37/02;A61K37/26;C07K7/40;C07K7/58;A23K1/165;

  • 国家 EP

  • 入库时间 2022-08-22 05:07:04

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