A METHOD AND COMPOSITIONS TO SCREEN COMPOUNDS FOR ENHANCEMENT OF THE CHOLINERGIC, DOPAMINERGIC AND SEROTONERGIC FUNCTION

摘要

A composition comprising a purified protein delivery enhancing an endogenous neurotransmitter induced by a stimulus, said neurotransmitter is selected from the group consisting of acetylcholine, dopamine or serotonin, said protein having a binding constant of affinity of at least 2, 9 U 0.8 nM vis-à-vis the 3,3-bis (4-pyridinylmethyl) -1-phénylindoline tritiated-2-one, determined by a Scatchard analysis, wherein said protein is trypsin sensitive and insensitive phospholipase C.