PROCESS FOR THE DETERMINATION OF SMALL QUANTITIES OF DRUGS, BODY SUBSTANCES OR OTHER CHEMICAL SUBSTANCES IN A BIOLOGICAL MATERIAL

摘要

process for the determination of small quantities of drugs, chemicals, or other chemical compounds in somatic biological material.is characterized by the fact that it connects the analog compound and to determine deutu00e9risu00e9 antibody in excess and coupled to a stationary phase based on polymeric material, and separating the two components of antibodies and the measurement by mass spectrometry the report is composed deutu00e9risu00e9 / the deutu00e9risu00e9 respectively composed of cross reaction, orin the case where we do not have available deutu00e9risu00e9 or appropriate cross reactive compound, used as internal standard compound, which is chemically similar to also added after the extraction containing antibodies and brought before the spectromu00e9t mass of a separation process.