Intermediary of the penetrating power for the transdermal administration of systemic active ingredients.

摘要

A composition for administering systematically active agents through the skin or other body membranes of humans and animals comprising an effective amount of a membrane penetration enhancer having the structural formula CHEM where R is H or a lower alkyl group having 1 - 4 carbon atoms, m is 5 - 7 and n is 0 - 17, and a systemically active agent is described. The use of an effective amount of a membrane penetration enhancer having the above mentioned structural formula in a method for administering systemically active agents through the skin or other body membranes of humans and animals in a transdermal device or formulation is also described.