Use of charged particles in the membrane filtration of fluid cell culture media.

摘要

There is provided a method of separating components of a liquid cell culture medium, involving mixing together the cell culture medium, first charged, particulate material and optionally second charged particulate material bearing a charge opposite that of the first charged, particulate material to form a suspension of matter in the medium and then recovering the suspended matter using membrane filtration. The method enables increased flow rates through the membrane filter and increased product recovery to be obtained.