orally applicable once daily extended release form for treatment of hypertension with diltiazemhydrochlorid.

摘要

Pharmaceutical units does contains 90-270mg diltiazem hydrochloride (I); has in vitro release rate 20-70%, 35-85% and 50-100% after 1,2 and 3.5 hr. , respectively, with at least 60% released after 5hr.; and are used for treatment of hypertension by once-daily oral administration. Pref. the dose contains 180mg (I) and releases at least85% after 5 hr.; im vitro.