A PROCESS FOR PRODUCING ENVELOPE PROTEIN OF JAPANESE ENCEPHALITIS VIRUS USING RECOMBINANT BACULOVIRUS; ENVELOPE PROTEINS,RECOMBINANT BACULOVIRUS AND VACCINES

摘要

Recombinant Baculovirus in which the cDNA encoding E protein derived from Japanese encephalitis virus is integrated into the genome region non-essential to proliferation of Baculovirus under control of the promoter is infected to insect cells such as Sf9 cells, derived from Spodoptera frugiperda and the infected cells are cultured to express E protein of Japanese encephalitis. This E protein is useful as vaccines or diagnostics.