DELIVERY SYSTEM FOR GROWTH OR MORPHOGENETIC FACTORS

摘要

A method of preparing a delivery system for a biologically active growth and morphogenetic factor by using chromatographic techniques and which includes introducing such biologically active factor into a chromatography column of appropriate dimensions which contains a porous carrier comprising a solid adsorbent selected for its specific affinity for such biologically active factor. In one embodiment porous hydroxyapatite is used as the carrier for bone morphogenetic proteins (ie BMPs). The delivery system is useful for inducing the formation of new bone in primates on implantation in the body. IMAGE