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Rapid miosis with control of intraocular pressure using a mixture of a cetylcholine and carbachol derivatives
Rapid miosis with control of intraocular pressure using a mixture of a cetylcholine and carbachol derivatives
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机译:通过使用十六烷基胆碱和卡巴胆碱衍生物的混合物控制眼压来快速缩小瞳孔
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摘要
Quick miosis with 24 hour control of intraocular pressure of patients undergoing extracapsular cataract extraction surgery is achieved by applying to the eyes of the patient during surgery acetylcholine as a first miotic agent and carbachol as a second miotic agent. Acetylcholine provides quick miosis while carbachol enhances the miotic effect while providing post-surgery control of intraocular pressure. The two miotic agents can be dissolved in a common saline carrier. The two agents can be combined in a unit dosage package by disposing acetylcholine in powder form in a first compartment and a solution of carbachol in a second compartment. The combined miotic agent of the invention is especially useful when substances which raise IOP such as viscoelastic agents are used during ocular surgery and/or with sensitive patients who enter the surgery with elevated pressure such as those suffering from glaucoma.
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